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This Week at NEJM.org | May 31, 2012 Listen to the Weekly Audio Summary Perspective Pathological Complete Response and Accelerated Drug Approval in Early Breast Cancer T.M. Prowell and R. Pazdur | May 30, 2012 | DOI: 10.1056/NEJMp1205737 Medication Reconciliation for Controlled Substances — An “Ideal” Prescription-Drug Monitoring Program J. Perrone and L.S. Nelson | May 30, 2012 | DOI: 10.1056/NEJMp1204493 Residents’ Response to Duty-Hour Regulations — A Follow-up National Survey B.C. Drolet, D.A. Christopher, and S.A. Fischer | May 30, 2012 | DOI: 10.1056/NEJMp1202848 Lost in Translation — ¿Cómo se dice, “Patient Protection and Affordable Care Act”? J.O. Breen | N Engl J Med 2012;366:2045-2047 | Published Online May 16, 2012 Home: Palliation for Dying Undocumented Immigrants R. Nuila | N Engl J Med 2012;366:2047-2048 Bisphosphonates for Osteoporosis — Where Do We Go from Here? M. Whitaker, J. Guo, T. Kehoe, and G. Benson | N Engl J Med 2012;366:2048-2051 | Published Online May 9, 2012 Continuing Bisphosphonate Treatment for Osteoporosis — For Whom and for How Long? D.M. Black and Others | N Engl J Med 2012;366:2051-2053 | Published Online May 9, 2012 Original Articles Drotrecogin Alfa (Activated) in Adults with Septic Shock V.M. Ranieri and Others | N Engl J Med 2012;366:2055-2064 | Published Online May 22, 2012 Outbreak of Salmonellosis Linked to Live Poultry from a Mail-Order Hatchery N.H. Gaffga and Others | N Engl J Med 2012;366:2065-2073 Preoperative Chemoradiotherapy for Esophageal or Junctional Cancer P. van Hagen and Others | N Engl J Med 2012;366:2074-2084 Childhood Outcomes after Hypothermia for Neonatal Encephalopathy S. Shankaran and Others | N Engl J Med 2012;366:2085-2092 Special Article Nighttime Intensivist Staffing and Mortality among Critically Ill Patients D.J. Wallace and Others | N Engl J Med 2012;366:2093-2101 | Published Online May 21, 2012 Review Articles Current Concepts: Drowning D. Szpilman, J.J.L.M. Bierens, A.J. Handley, and J.P. Orlowski | N Engl J Med 2012;366:2102-2110 200th Anniversary Article: Two Hundred Years of Cancer Research V.T. DeVita, Jr., and S.A. Rosenberg | May 30, 2012 | DOI: 10.1056/NEJMra1204479 Images in Clinical Medicine Splenic Spirals S. Patadia and S.S. Vasanawala | N Engl J Med 2012;366:2111-2111 Palisaded Neutrophilic and Granulomatous Dermatitis M. Singh and N. Comfere | N Engl J Med 2012;366:e33 Case Records of the Massachusetts General Hospital Case 17-2012: A 54-Year-Old Man with Visual-Field Loss and a Mass in the Brain T.T. Batchelor, A.G. Sorensen, and D.N. Louis | N Engl J Med 2012;366:2112-2120 Editorials Septic Shock — Evaluating Another Failed Treatment R.P. Wenzel and M.B. Edmond | N Engl J Med 2012;366:2122-2124 | Published Online May 22, 2012 Intensive Enough? V. Campbell | N Engl J Med 2012;366:2124-2125 | Published Online May 21, 2012 Clinical Implications of Basic Research The Spread of Neurodegenerative Disease J. Hardy and T. Revesz | N Engl J Med 2012;366:2126-2128 Correspondence Colorectal-Cancer Screening Intratumor Heterogeneity and Branched Evolution Pasireotide in Cushing's Disease The Emerging Threat of Untreatable Gonococcal Infection Lower-Extremity Lymphedema and Elevated Body-Mass Index Corrections Prostate-Cancer Mortality at 11 Years of Follow-up Dysfunction of the Diaphragm Primary Hyperparathyroidism Image Challenge What is the diagnosis? Submit Answer » Browse All Online First Articles » Trends: Most Viewed (Last Week) Colorectal-Cancer Incidence and Mortality with Screening Flexible Sigmoidoscopy May 21, 2012 Aspirin for Preventing the Recurrence of Venous Thromboembolism May 24, 2012 Nighttime Intensivist Staffing and Mortality among Critically Ill Patients May 21, 2012 More Trends Subscribe to NEJM, Now Includes NEJM iPad Edition & Bonus Gifts NEJM is celebrating its 200th anniversary! Subscribe today and get subscriber-only access to NEJM.org and the NEJM iPad Edition. Your subscription includes 20 FREE online CME exams (earn up to 20 CME Credits) and 50 FREE article views from the NEJM Archive 1812–1989, PLUS your anniversary gift of 200 additional free CME exams and 200 bonus archive views. Subscribe Today! ASSOCIATE PROGRAM DIRECTOR — MASSACHUSETTS Internal Medicine Residency Training Program, Mount Auburn Hospital, Cambridge, Massachusetts. 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