Stig Östlund

torsdag, mars 21, 2013

NEJM March 21

 



Table of contents for

Current Issue

March 21, 2013 Vol. 368 No. 12

Audio Summary of this Issue


Perspective

1073-1075
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  • Audio
In response to events in Pakistan that led to the deaths of eight vaccination workers and the suspension of polio-eradication efforts, deans of U.S. public health schools advocate refraining from disguising military or intelligence actions as public health activities.


1075-1076
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1077-1081
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Original Articles

1083-1091


1092-1100
 
1101-1110
Earlier studies suggested that the response to platinum treatment in lung cancer might be predicted according to the presence or absence of the DNA repair enzyme ERCC1. This study shows that the available antibodies do not predict response because they may detect nonfunctional enzymes.


1111-1120
Development of a malaria vaccine is a high global health priority. This report assessed the effect of waning vaccine-induced immunity and the level of malaria exposure on vaccine efficacy in Kenyan children who received the RTS,S/AS01E vaccine and were followed for 4 years.

Special Article

1121-1130

Clinical Therapeutics

1131-1139
A woman receives a diagnosis of diffuse large B-cell lymphoma; a standard chemotherapy regimen is recommended. Use of prophylactic granulocyte CSF is considered. G-CSF stimulates proliferation of neutrophil progenitors and release of mature neutrophils from bone marrow.

Images in Clinical Medicine

1140
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A 47-year-old woman was referred for bone pain and abnormal findings on radiography. The patient reported that for the past 17 years she has habitually consumed a pitcher of tea made from 100 to 150 tea bags daily.
Av alla drycker är kaffe den bästa och det kan aldrig bli för mycket (känns det iaf som). Betänk dessutom en morgon utan kaffedrickning...huga!


e15
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Case Records of the Massachusetts General Hospital

1141-1150
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Editorial

1152-1153
In approximately 30% of young survivors of stroke, no clear cause is identified despite a thorough evaluation.1 Patent foramen ovale is found on transesophageal echocardiography in about half of these patients, as compared with approximately 25% of the ...

Clinical Implications of Basic Research

1154-1156
Doxorubicin and other anthracyclines are used to treat cancer, yet they elevate the risk of heart failure. A recent study provides insight into how doxorubicin causes heart failure and points to research strategies for reducing risk.

Correspondence

1157-1160


1160-1161
To the Editor: Tolwani (Dec. 27 issue)1 recommends continuous renal-replacement therapy over intermittent hemodialysis (for 4 hours per day) for a patient with postoperative acute kidney injury. We believe that there is an even better option: prolonged ...


1161-1163
To the Editor: Hartnett and Penn (Dec. 27 issue)1 describe mechanisms by which changes in oxygen tension contribute to retinopathy of prematurity. A major cause of vision loss in these patients remains retinal vasoproliferation into the vitreous, which ...


1163
To the Editor: In his Perspective article, Jost (Jan. 3 issue)1 discusses insurance coverage of contraceptives. We wish to highlight another health benefit associated with such coverage: the use of contraceptives by patients who need to use teratogenic ...


1163-1165
To the Editor: In the Case Record, Nejad et al. (Dec. 20 issue)1 describe alcohol withdrawal. Although we appreciate the detailed discussion of the need to evaluate for precipitating medical issues, we have concerns regarding the authors' suggestions for ...


1165-1166



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