Stig Östlund

torsdag, november 24, 2011


http://www.nejm.org/
 This Week at NEJM.org  November 24, 2011

Perspective

Making Sense of the New Cervical-Cancer Screening Guidelines
S. Feldman November 23, 2011  DOI: 10.1056/NEJMp1112532

Prostate-Cancer Screening — What the U.S. Preventive Services Task Force Left Out
A.S. Brett and R.J. Ablin - N Engl J Med 2011;365:1949-1951 - Published Online October 26, 2011

One Man at a Time — Resolving the PSA Controversy
M.F. McNaughton-Collins and M.J. Barry - N Engl J Med 2011;365:1951-1953 - Published Online October 26, 2011

Stratifying Risk — The U.S. Preventive Services Task Force and Prostate-Cancer Screening
F.H. Schröder - N Engl J Med 2011;365:1953-1955 - Published Online October 26, 2011

The Medical College Admission Test — Toward a New Balance
J.L. Dienstag - N Engl J Med 2011;365:1955-1957

Original Articles

Comparative Effectiveness of Weight-Loss Interventions in Clinical Practice - L.J. Appel and Others - N Engl J Med 2011;365:1959-1968 - Published Online November 15, 2011

A Two-Year Randomized Trial of Obesity Treatment in Primary Care Practice - T.A. Wadden and Others - N Engl J Med 2011;365:1969-1979 - Published Online November 14, 2011

Abciximab and Heparin versus Bivalirudin for Non–ST-Elevation Myocardial Infarction
A. Kastrati and Others - N Engl J Med 2011;365:1980-1989 - Published Online November 13, 2011

Daily or Intermittent Budesonide in Preschool Children with Recurrent Wheezing
R.S. Zeiger and Others - N Engl J Med 2011;365:1990-2001

Special Article

Emergency Hospitalizations for Adverse Drug Events in Older Americans
D.S. Budnitz, M.C. Lovegrove, N. Shehab, and C.L. Richards - N Engl J Med 2011;365:2002-2012

Clinical Practice

Screening for Prostate Cancer
R.M. Hoffman - N Engl J Med 2011;365:2013-2019 - Published Online October 26, 2011

Images in Clinical Medicine

Neurofibromatosis
A. Ibrahim (Inte Zlatan!) and M.E. Asuku - N Engl J Med 2011;365:2020-2020

Cysticercosis
I.R. da Silva Ferreira and S.P. Magalhaes - N Engl J Med 2011;365:e41

Case Records of the Massachusetts General Hospital

Case 36-2011: A 93-Year-Old Woman with Shortness of Breath and Chest Pain E.L. Senecal, K. Rosenfield, A.E. Caldera, and J.J. Passeri - N Engl J Med 2011;365:2021-2028

Editorial

Obesity Treatment in Primary Care — Are We There Yet?
S.Z. Yanovski - N Engl J Med 2011;365:2030-2031 - Published Online November 15, 2011

Correspondence

- Prevention of Intraoperative Awareness
- Reduced Lung-Cancer Mortality with CT Screening
- Mendelian Disorders of Membrane Trafficking
- Acutely Injured Patients on Dabigatran

 Corrections

- Decompressive Craniectomy in Diffuse Traumatic Brain Injury
-A Prospective Natural-History Study of Coronary Atherosclerosis
____________________________________________________________________________


Question



This patient presented with a 1-day history of fever, acute painful symmetric polyarthritis, abdominal pain, and hematemesis. What is the diagnosis?


Bacterial endocarditis *  Henoch-Schönlein purpura * Purpura fulminans * Rheumatic fever * Rocky Mountain spotted fever

Bacterial endocarditis: bakteriell endokardit, oftare kallat infektiös endokardit är en infektion i hjärtklaffarna eller beklädnad av hjärtat kamrarna. Det inträffar när bakterier från munnen, hud, övre luftvägarna, tarmkanalen eller urinvägarna kommer in i blodomloppet och lägger till hjärtat ...
Henoch-Schönlein purpura: Henoch-Schönleins purpura (HSP) är en sjukdom som oftast drabbar pojkar 3-10 år, men även drabbar annat klientel. HSP ger karakteristiska utslag i form av...
Rheumatic fever
Purpura fulminans:  purpura ful´minans nonthrombocytopenic purpura seen mainly in children, usually after an infectious disease, marked by fever, shock, anemia, and sudden, rapidly spreading symmetrical skin hemorrhages of the lower limbs, often associated with extensive intravascular thromboses and gangrene.

Rocky Mountain spotted fever: Rocky Mountain spotted fever is a serious, generalized infection that is usually spread to people by the bite of infected ticks. The disease gets its name from the Rocky Mountain area where it was first identified --- People with Rocky Mountain spotted fever get a sudden fever (which can last for 2 or 3 weeks), severe headache, tiredness, deep muscle pain, chills, nausea, and a characteristic rash ...

Detta var svårt även om Google alltid finns tillhanda.
'Rheumatic fever' = inga problem, men t.ex. 'Purpura fulminans'... Och 'Rocky Mountain spotted fever' hade man ju ingen aaaning om fanns, men Googles engelska info vara bra (anm.: har jag glömt i morgon).
Har under googlandet sett en del mindre trevliga bilder på olika utslag som människan kan drabbas av; man må vara mycket tacksam att ha sluppit sådant.
Bilden: Min trogne vän Google menar att det är 'Henoch-Schönlein purpura'.
_________________________________________________________________________________________


In the United States, approximately 90% of prostate cancers are detected by means of screening.

How common is prostate cancer in older men?

Autopsy series suggest that 30% of men older than 50 years of age and 70% of those older than 70 years of age have prostate cancer. The great majority of men with a diagnosis of prostate cancer die from other causes.

Approximately how many men need to be screened for prostate cancer to prevent one death?

The European Randomized Study of Screening for Prostate Cancer, conducted in nine European centers, randomly assigned 182,160 men who were 50 to 74 years of age to PSA screening every 4 years or usual care (no PSA screening). During a median follow-up of 9 years, prostate cancer was detected in 8.2% of the screened subjects as compared with 4.8% of the control subjects (a 71% increase). The absolute difference in mortality between groups was only 0.7 deaths per 1000 men, suggesting that 1410 men would need to be screened approximately twice over a period of 9 years to prevent 1 death from prostate cancer.

Prostate-Cancer Screening Guidelines  >> http://www.nejm.org/action/showImage?doi=10.1056/NEJMcp1103642&iid=t02&query=BUL

Bloggarkiv