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This Week at NEJM.org | July 5, 2012 Listen to the Weekly Audio Summary Perspective The Dénouement of the Supreme Court’s ACA Drama R.M. Landers | July 2, 2012 | DOI: 10.1056/NEJMp1206847 The Road Ahead for the Affordable Care Act J.E. McDonough | July 2, 2012 | DOI: 10.1056/NEJMp1206845 Automated Hovering in Health Care — Watching Over the 5000 Hours D.A. Asch, R.W. Muller, and K.G. Volpp | N Engl J Med 2012;367:1-3 | Published Online June 20, 2012 Geographic Variation in Access to Care — The Relationship with Quality D.C. Radley and C. Schoen | N Engl J Med 2012;367:3-6 | Published Online June 13, 2012 Justice for Injured Research Subjects C. Elliott | N Engl J Med 2012;367:6-8 How Far Do You Go? Intensive Care in a Resource-Poor Setting A.P. Eyssallenne | N Engl J Med 2012;367:8-9 Delays and Difficulties in Assessing Metal-on-Metal Hip Implants J.P. Rising, I.S. Reynolds, and A. Sedrakyan | N Engl J Med 2012;367:e1 | Published Online June 20, 2012 Original Articles Eltrombopag and Improved Hematopoiesis in Refractory Aplastic Anemia M.J. Olnes and Others | N Engl J Med 2012;367:11-19 Estimating Glomerular Filtration Rate from Serum Creatinine and Cystatin C L.A. Inker and Others | N Engl J Med 2012;367:20-29 Cognitive Trajectories after Postoperative Delirium J.S. Saczynski and Others | N Engl J Med 2012;367:30-39 A Pooled Analysis of Vitamin D Dose Requirements for Fracture Prevention H.A. Bischoff-Ferrari and Others | N Engl J Med 2012;367:40-49 Clinical Therapeutics Shock-Wave Lithotripsy for Renal Calculi M.S. Pearle | N Engl J Med 2012;367:50-57 Review Article 200th Anniversary Article: Two Centuries of Neurology and Psychiatry in the Journal A.H. Ropper | N Engl J Med 2012;367:58-65 Images in Clinical Medicine Steeple Sign of Croup C.-C. Huang and S.-L. Shih | N Engl J Med 2012;367:66-66 Dynamic Extrathoracic Airway Obstruction D. Pradhan and K. Berger | N Engl J Med 2012;367:e2 Clinical Problem-Solving At a Loss J.F. Merola and Others | N Engl J Med 2012;367:67-72 Editorials A Promising New Treatment for Refractory Aplastic Anemia D. Metcalf | N Engl J Med 2012;367:74-75 Improving the Estimating Equation for GFR — A Clinical Perspective M.R. Weir | N Engl J Med 2012;367:75-76 Vitamin D — Baseline Status and Effective Dose R.P. Heaney | N Engl J Med 2012;367:77-78 Sounding Board Surgical Margins in Lumpectomy for Breast Cancer — Bigger Is Not Better M. Morrow, J.R. Harris, and S.J. Schnitt | N Engl J Med 2012;367:79-82 Correspondence CT Angiography for Possible Acute Coronary Syndrome New Aspects of Membranoproliferative Glomerulonephritis Endoscopic Treatment of Primary Vesicoureteral Reflux The Perpetual Challenge of Infectious Diseases Autopsy Findings in Children with Hand, Foot, and Mouth Disease Corrections Predicting Risk of Progressive Multifocal Leukoencephalopathy from Natalizumab To Be 17 Again — Anti–Interleukin-17 Treatment for Psoriasis Stenting versus Aggressive Medical Therapy for Intracranial Arterial Stenosis Image Challenge <><> What is the diagnosis? Submit Answer » Browse All Online First Articles » Trends: Most Viewed (Last Week) A Reader's Guide to 200 Years of the New England Journal of Medicine January 5, 2012 Medical Mystery — The Answer August 19, 2004 The Burden of Disease and the Changing Task of Medicine June 21, 2012 More Trends Subscribe to NEJM, Now Includes NEJM iPad Edition & Bonus Gifts NEJM is celebrating its 200th anniversary! Subscribe today and get subscriber-only access to NEJM.org and the NEJM iPad Edition. Your subscription includes 20 FREE online CME exams (earn up to 20 CME Credits) and 50 FREE article views from the NEJM Archive 1812–1989, PLUS your anniversary gift of 200 additional free CME exams and 200 bonus archive views. Subscribe Today! INFECTIOUS DISEASE — MARYLAND Infectious Disease/Transplant physician at NIH (Bethesda, Maryland). The Clinical Monitoring Research Program (CMRP) of SAIC-Frederick, Inc. is responsible for providing clinical and scientific expertise and management support to the National Institute of Allergy and Infectious Diseases (NIAID), Division of Clinical Research (DCR). While supporting the Laboratory of Host Defenses, this position collaborates with the Principal Investigator on the clinical management of the intramural and multicenter clinical protocols that includes stem cell and gene therapies for treatment of primary immune deficiencies.... Looking for a new practice opportunity? View this job and other listings at NEJM CareerCenter. Search now for both permanent and locum tenens jobs in many specialties. Follow us

News Review From Harvard Medical School  (July 5)-- Bigger Vitamin D Dose May Lower Fractures Taking larger doses of vitamin D may reduce the risk of hip fractures in older women by 30%, a new study finds. The study combined the results of 11 prior studies. They included a total of 31,022 people. More than 90% were women. All were 65 or older. People were randomly assigned to take vitamin D pills or placebo (fake) pills. The new analysis found that the risk of hip fracture was 10% lower for those assigned to receive the real vitamin D pills. That difference was so small it could have been caused by chance. But the researchers also looked at measurements of how much vitamin D people actually took. This included extra vitamin D that people took on their own. Hip fracture risk was 30% lower in those who took at least 800 international units a day. The New England Journal of Medicine published the study. HealthDay News wrote about it July 4.